Netcare 911 paramedics and other services responded to an accident on West Road in President Park, Midrand Saturday evening.
Upon their arrival on scene they found that a motor vehicle and minibus had collided head-on resulting in five people sustaining injuries ranging from moderate to serious.
The injured people were treated on scene before they were transported to a nearby hospital for further medical care.
Exact detail to the cause of the accident and preceding events will remain the subject of a police investigation.